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Reverse Shapiro's Syndrome:Hirayama
K. , et al, Arch Neurol 51:494-49694., , 1994
See this aricle in Pubmed

Article Abstract
No neurologic or physical abnormalities were noted beside the callosal agenesis.Neuroimaging examinations could not reveal any structural abnormality of the diencephalon.Endocrinological examinations and electroencephalograms were found to be normal.The hyperthermia returned to normal by a small dose of levodopa,but a larger dose reversed the hyperthermia to hypothermia.These observations suggest that the hyperthermia observed in this case may have been caused by the dopaminergic denervation of the hypothalamic thermoregulatory center, resulting in the supersensitivity of its dopaminergic receptors.
 
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dopamine receptor
hyperthermia
L-dopa
pyruvate-kinase deficiency anemia
treatment of neurologic disorder

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